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Image Search Results
Journal: Microorganisms
Article Title: Phylogenetic Characteristics and High Prevalence of a Merbecovirus in Hedgehogs from Greenspace of a Metropolis, China
doi: 10.3390/microorganisms14010083
Figure Lengend Snippet: Analysis of the BJ-HKU31 spike (S) protein. ( A ) Detection of a possible recombination event was conducted using bootscan analysis. A whole genome sequence similarity plot was performed using Simplot (v3.5.1), with a window size of 1000 bp and a step size of 200 bp. A bat coronavirus (GenBank accession no. KC869678 ) served as the query sequence and was compared against other coronaviruses, including Ea -HedCoV HKU31 (red, this study), BtVs-BetaCoV/SC2013 (green), and bat coronavirus HKU4 (yellow). ( B ) Amino acid sequence alignments of receptor-binding domain (RBD) sequences of hedgehog coronaviruses. The sequence of MERS-CoV (GenBank accession no. NC_019843 ) was used as the reference sequence. Different colors are used to highlight distinct residues, red asterisks mark conserved residues (functionally critical in MERS-CoV).
Article Snippet: To assess potential recombination events in the genomes of hedgehog CoVs identified in this study,
Techniques: Sequencing, Binding Assay